Ψ PSORS1C2 - Tursiops truncatus
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_DIIZDM | Tursiops truncatus | LOF (frameshift, premature stop, ss) | Full | Yes | Genomic | XM_019927173.2 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Functional | "The identification of cetaceans as “natural knockout animals” for PSORS1C2 supports the hypothesis that PSORS1C2 has a primary function in terminal differentiation of keratinocytes and skin barrier function in a dry environment." | 10.1111/exd.13272 |
| Mutation Description | "The PSORS1C2 genes of all 5 investigated species of cetaceans, carry, besides additional mutations in exon 2 (Suppl. Fig. S4), a common frame shift mutation in exon 1 that abolishes the expression of a PSORS1C2 in cetaceans (Fig. 2b)." | 10.1111/exd.13272 |