Ψ AMELX - Balaena mysticetus

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_D75PR5 Balaena mysticetus LOF (frameshift, premature stop, ss) Full No Genomic

Statements

Type Excerpt DOI
Functional "Seven of these genes are enamel specific (ACP4, AMBN, AMELX, AMTN, ENAM, KLK4, MMP20) and two are related to dentin/tooth formation (...)." 10.1016/j.ympev.2022.107463
Mutation Description "Among these is a 1-bp insertion in exon 11 that is shared by all four balaenids. AMELX has one or more inactivating mutations in all mysticetes except for Balaenoptera musculus and Eubalaena glacialis." 10.1016/j.ympev.2022.107463
Timing of Loss "34,62 MYA" 10.1016/j.ympev.2022.107463

Curator Observations

See table 3 for details regarding mutations.