Mutation Description |
"In addition to taxa with deleted or mostly deleted copies of MC5R, we also discovered inactivating mutations in Loxodonta africana, Mammuthus primigenius (woolly mammoth), Ceratotherium simum (white rhinoceros), Galeopterus variegatus (Sunda colugo), Nomascus leucogenys (northern white-cheeked gibbon), and Pongo abelii (Sumatran orangutan) (Fig. 4)." |
10.1016/j.ympev.2017.12.010 |
Mutation Description |
"The rhinocerotid C. simum has a premature stop codon at positions 73-75." |
10.1016/j.ympev.2017.12.010 |
Phenotypic |
"Here, we show that MC5R has either been deleted from the genome or inactivated in multiple mammalian lineages that have lost their sebaceous glands or have degenerative sebaceous glands
including fully aquatic cetaceans and West Indian manatee, pangolins, African elephant, and white rhinoceros." |
10.1016/j.ympev.2017.12.010 |