Ψ UCP1 - Physeter catodon
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_BZIDO4 | Physeter catodon | LOF (frameshift, premature stop, ss) | Full | No | Genomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Functional | "Genes associated with […] heat production by brown adipose tissue (UCP1) had unique changes that may contribute to marine mammal thermoregulation." | 10.1073/pnas.2106080118 |
| Mutation Description | "[…] our newly sequenced cetacean genomes suggest that UCP1 is reduced to a pseudogene in baleen whales and lost in toothed whales" | 10.1073/pnas.2106080118 |
| Phenotypic | "[…] the integrity of UCP1 gene affects the fate of brown adipocyte" | 10.1073/pnas.2106080118 |
Curator Observations
See Sup figure 12
Related Glosses
| GL_ID | Symbol | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|---|
| GL_6XBDJJ | UCP1 | Physeter catodon | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.1126/sciadv.1602878 |