| Functional |
"Li et al. (2014) [47] investigated Tas2rs gene repertoires in vertebrates,
and they demonstrated that dietary toxins are a major selective force shaping the diversity of the Tas2r repertoire." |
10.1186/s12862-014-0218-8 |
| Mutation Description |
"In Tas2r2, Tas2r5 and Tas2r16, we found shared ORF-disrupting mutations and/or premature stop codons in all toothed whales, such as a 1 bp or a 2 bp deletion in Tas2r2 (Additional file 3: Figure S5), a shared TGA premature stop codon in Tas2r5 (Additional file 3: Figure S7), and a 4 bp deletion in Tas2r16 (Additional file 3: Figure S8), suggesting that the functional loss of these genes happened in the common ancestor of toothed whales." |
10.1186/s12862-014-0218-8 |
| Mutation Description |
"Based on sequence alignments against cow (Bos taurus) homologues, we identified multiple ORF-disrupting indels and premature stop codons in Tas1r1, Tas1r2, Pkd2l1 and in ten Tas2rs scattered among cetacean branches." |
10.1186/s12862-014-0218-8 |
| Timing of Loss |
"However, we could not exclude the possibility that the pseudogenization event in Tas2r2 might have occurred in the ancestor of all cetaceans, although we failed to amplify the whole Tas2r2 sequence in the common minke whale (Balaenoptera acutorostrata)." |
10.1186/s12862-014-0218-8 |
| Other |
"SEE "Additional file 3: Figures S1-S11. Indels and premature stop codons in Pkdl21, Tas1r1, Tas1r2, Tas2r1-3, Tas2r5, Tas2r16, Tas2r38-39, and Tas2r60." |
10.1186/s12862-014-0218-8 |