| Functional |
"Previous study has reported that deficient for K6B (epithelial keratins) may contributed to the absence of hair and nail in mice." |
10.1186/s12983-017-0225-x |
| Methodology & Validation |
"We first identified α-keratin gene repertoires in the cow (Bos taurus) (coverage 7×,Btau_4.6.1) [...] taking all the known α-keratin gene sequences of human as queries using BLASTN and TBLASTN algorithm. [...] The putative α-keratin genes in the cow were then taken as queries to explore the α-keratin multigene family in the genome of 11 marine mammals, including [...] bowhead whale (Balaena mysticetus, coverage 150×, http://www.bowheadwhale.org/downloads/)." |
10.1186/s12983-017-0225-x |
| Phenotypic |
"Our results show an apparent reduction in the α-keratin gene repertoire and increased rate of pseudogenization in cetaceans when compared to terrestrial counterparts, which may be associated with their hairless phenotype." |
10.1186/s12983-017-0225-x |
| Other |
"However, some genes within one specie grouped together rather than with the members of the same family in other species, such as among the genes of K31, K33A, K33B and K34 in type I, as well as the K6A, K6B, K6C, K81, K83, K87 and K86 in the type II." |
10.1186/s12983-017-0225-x |