| Functional |
"Seven of these genes are enamel specific (ACP4, AMBN, AMELX, AMTN, ENAM, KLK4, MMP20) and two are related to dentin/tooth formation (...)." |
10.1016/j.ympev.2022.107463 |
| Mutation Description |
"Of the seven enamel genes, three (ACP4, KLK4, MMP20) were found to have inactivating mutations that are shared by all mysticetes. ACP4 has a 1-bp deletion in exon 4; KLK4 has a 1-bp deletion in exon 3; and MMP20 has a SINE insertion in exon 2." |
10.1016/j.ympev.2022.107463 |
| Other |
"Remnants of this insertion range from 302 to 324 bp in different mysticete species with assembled genomes, and all possible reading frames of this SINE insertion contain premature stop codons that would result in a severely truncated MMP20 protein (Meredith et al., 2011a)." |
10.1016/j.ympev.2022.107463 |