Functional |
"In mammals, Mtnr1a and Mtnr1b receptors are involved in the response of the clock machinery to melatonin stimulation (Reppart et al. 1996)." |
10.1007/s00239-021-10025-1 |
Mutation Description |
"For Mtnr1a, a total of 44 species exhibited a PseudoIndex higher than 2 (Online Resource 3), yet manual curation revealed ORF-disrupting mutations only in pangolins (validated through SRA Projects; Online Resource 12) (Huelsmann et al. 2019), Hawaian monk seal (Neomonachus schauinslandi) and D. dugon (Online Resource 4)." |
10.1007/s00239-021-10025-1 |
Methodology & Validation |
"Mutational validation was performed through retrieval of raw sequencing reads in (at least) two independent Sequence Read Archive (SRA) projects (when available)." |
10.1007/s00239-021-10025-1 |