| Mutation Description |
"Regarding Aanat, in agreement with Yin et al. (2021), we found numerous ORF-disrupting mutations, including a conserved 1-nucleotide deletion in exon 1 in Armadillos and a conserved 2-nucleotide deletion in exon 3 in Sloths (Fig. 2;
Online Resource 4)." |
10.1007/s00239-021-10025-1 |
| Methodology & Validation |
"The identified mutations were next
validated by searching at least one ORF-disruptive mutation
per species in the corresponding SRAs; reads corroborating
the identified mutations were systematically found (Online
Resource 5)." |
10.1007/s00239-021-10025-1 |
| Timing of Loss |
"Interestingly, the mutational profile of melatonin synthesis and signaling genes within Xenarthra, supports the occurrence of independent inactivation events among Xenarthran orders (Cingulata and Pilosa)." |
10.1007/s00239-021-10025-1 |
| Phenotypic |
"Our results strongly suggest a complete landscape of gene loss in Xenarthra, which further reinforce reports suggesting the lack of a pineal gland in several members of this superorder." |
10.1007/s00239-021-10025-1 |