Ψ Cym - Rhinopithecus roxellana
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_6VSEN9 | Rhinopithecus roxellana | LOF (frameshift, premature stop, ss) | Full | Yes | Genomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "Interestingly, a cross species analysis in Hominoidea and Cercopithecoidea uncovers a conserved single mutation that spans throughout all analysed Cmy-like sequences, namely a termination codon in exon 5." | 10.1016/j.ympev.2017.08.014 |
| Mutation Description | "ORF-disrupting mutations were also found in the sister clade, the Cercopithecoidea. We found no remnants of exon 3 and exon 4 in the corresponding genomic region suggesting a marked Cmy erosion by the complete deletion of these exons in these species, in addition to several observed ORF abolishing mutations (Fig. 1)." | 10.1016/j.ympev.2017.08.014 |
Curator Observations
Although only genomic evidence is provided the conservation of the observed mutations in Hominoidea strongly supports that the pseudogenization in this species is fixed.