Ψ ALDOA - Physeter catodon
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_61PL5X | Physeter catodon | LOF (frameshift, premature stop, ss) | Full | Yes | Multiple individual SRA | XM_024123635.3 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "We first established that Aldoa_v2 emerged in the ancestor of placental mammals and is expressed uniquely in testis (Figure 1C). Moreover, we deduced the presence of an ORF-disrupting mutation within the sperm-specific exon in all of the examined Cetacea species (Figure 1C; additional figshare link in Key resources table)." | 10.1016/j.cub.2021.05.062 |
Curator Observations
Aldoa_v2 is a splice isoform of Aldoa gene that is specifically expressed in testis and differs from V1 by including an additional exon at the start of the gene, where the LOF is located.