Ψ DGAT2L6 - Phataginus tricuspis

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_4MSDFE Phataginus tricuspis LOF (frameshift, premature stop, ss) Full No Single individual SRA

Statements

Type Excerpt DOI
Mutation Description "In P. tricuspis, a set of nucleotide deletions, premature stop codons, and a validated single-nucleotide insertion were identified" 10.1007/s00239-023-10118-z
Timing of Loss "Such mutational patterns indicate an independent Dgat2l6 erosion among pangolin lineages." 10.1007/s00239-023-10118-z
Phenotypic "Ancestral (i.e., Awat1, Awat2, Aadacl3) and independent (i.e., Dgat2l6) pseudogenization events in genes associated with epidermal lipids and sebum production strongly suggest a progressive impairment of the sebum-producing molecular machinery in pangolin lineages." 10.1007/s00239-023-10118-z