| Functional |
"OMP is a single-copygene that is strongly expressed in vertebrate OR neurons(Reisert etal.,2007), and this implies a critical role in olfaction. Functional studies and knockouts of OMP in mouse corroborate this role (Buiakova etal.,1996; Youngentob etal.,2001,2003)." |
10.1016/j.ympev.2017.01.020 |
| Mutation Description |
"Physeter macrocephalus (sperm whale) has a start codon mutation (ATG to GTG) that was confirmed by sequence reads in the SRA. The nearest alternative start codon in P. macrocephalus is 25 codons downstream. By contrast, all non- cetaceans have putative ATG start codons at the same codon position that is mutated to GTG in P. macrocephalus." |
10.1016/j.ympev.2017.01.020 |
| Phenotypic |
"Our results favor the echolocation-priority hypothesis for the evolution of OMP in odontocetes, and further suggest that two other olfactory-specific genes, CNGA2 and CNGA4, are inactivated in some odontocetes." |
10.1016/j.ympev.2017.01.020 |