Ψ MSS51 - Physeter catodon

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_0XPCAM Physeter catodon LOF (frameshift, premature stop, ss) Full Yes Multiple individual SRA XM_007110854.4

Statements

Type Excerpt DOI
Functional "Another example is MSS51, a gene that is predominantly expressed in fast glycolytic fibers of the skeletal muscle." 10.1126/sciadv.aaw6671
Phenotypic "Inactivation of MSS51 in muscle cell lines directs muscle energy metabolism toward beta-oxidation of fatty acids. MSS51 was lost in the cetacean stem lineage (fig. S20 and table S2), suggesting that muscle metabolism may be largely fueled by fatty acids, which would be consistent with a high intramuscular lipid content in cetaceans." 10.1126/sciadv.aaw6671

Curator Observations

See reference supplementary material.