Ψ MC5R - Galeopterus variegatus

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_0VDMTJ Galeopterus variegatus LOF (frameshift, premature stop, ss) Full No Genomic

Statements

Type Excerpt DOI
Mutation Description "In addition to taxa with deleted or mostly deleted copies of MC5R, we also discovered inactivating mutations in Loxodonta africana, Mammuthus primigenius (woolly mammoth), Ceratotherium simum (white rhinoceros), Galeopterus variegatus (Sunda colugo), Nomascus leucogenys (northern white-cheeked gibbon), and Pongo abelii (Sumatran orangutan) (Fig. 4)." 10.1016/j.ympev.2017.12.010
Mutation Description "The dermopteran G. variegatus has a premature stop codon at positions 241-243." 10.1016/j.ympev.2017.12.010
Phenotypic "Inactivating mutations in MC5R also occur in aardvark and colugo, both of which have derived skin properties, i.e., thick skin in aardvarks, lack of arrector pili muscles in colugos." 10.1016/j.ympev.2017.12.010