Ψ GAPDHS - Physeter catodon

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_0SWHWM Physeter catodon LOF (frameshift, premature stop, ss) Full Yes Multiple individual SRA XM_028487311.2

Statements

Type Excerpt DOI
Mutation Description "Among these, a single splice site mutation was shared across all the examined Odontoceti species, with exception of the early diverging beaked (Ziphiidae) and sperm whales (Physeteridae and Kogiidae), which display independent inactivating mutations (Figure 1A)." 10.1016/j.cub.2021.05.062

Curator Observations

Gapdhs (glyceraldehyde-3-phosphate dehydrogenase spermatogenic) is a sperm-specific glycolytic enzyme that plays a crucial role in the glycolysis pathway.