Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| ACSM3 acyl-CoA synthetase medium chain family member 3 | SA , SAH | Homo sapiens | 23 | protein-coding | ACSM4 , ACSM5 , ACSM1 , ACSM2A , ACSM2B , ACSM6 | 6.2.1.17 , 6.2.1.2 | 145505 |
Summary
Enables butyrate-CoA ligase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid biosynthetic process. Located in mitochondrion. Implicated in IgA glomerulonephritis. Biomarker of ulcerative colitis. [provided by Alliance of Genome Resources, Apr 2022]
GeneOntology
Gene Loss events - ACSM3 (4 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_2SONQX | Balaenoptera acutorostrata | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_6Y6UVJ | Physeter catodon | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_EMKX9E | Tursiops truncatus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_WVVRQP | Orcinus orca | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | Cetacea | 10.1126/sciadv.aaw6671 |