Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| TCHH trichohyalin | THH , THL , TRHY , UHS3 | Homo sapiens | 3 | protein-coding | 190370 |
Summary
The protein encoded by this gene forms crosslinked complexes with itself and keratin intermediate filaments to provide mechanical strength to the hair follicle inner root sheath. The encoded protein also is important for structural integrity of the filiform papillae of the tongue. Defects in this gene are a cause of uncombable hair syndrome. [provided by RefSeq, Feb 2017]
Gene Loss events - TCHH (3 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_0YLIAV | Phocoena sinus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1038/s41598-021-91863-3 |
| GL_OJBTND | Tursiops truncatus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1038/s41598-021-91863-3 |
| GL_T18ZAE | Balaenoptera acutorostrata | Artiodactyla | Other | Full | No | 10.1038/s41598-021-91863-3 |