Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| NAA50 N-alpha-acetyltransferase 50, NatE catalytic subunit | SAN , MAK3 , NAT5 , NAT13 , NAT5P , NAT13P , hNaa50p | Homo sapiens | 5 | protein-coding | 2.3.1.258 | 610834 |
Summary
Enables histone H4 acetyltransferase activity and peptide alpha-N-acetyltransferase activity. Involved in N-terminal protein amino acid acetylation; establishment of mitotic sister chromatid cohesion; and mitotic sister chromatid cohesion, centromeric. Located in cytosol and nucleolus. Part of NatA complex. [provided by Alliance of Genome Resources, Jan 2025]
Gene Loss events - NAA50 (2 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_2IIVYC | Phocoena sinus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1038/s41598-021-91863-3 |
| GL_PQE7RO | Tursiops truncatus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1038/s41598-021-91863-3 |