Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| HRNR hornerin | FLG3 , S100A16 , S100a18 | Homo sapiens | 3 | protein-coding | FLG2 , FLG | 616293 |
Summary
Predicted to enable calcium ion binding activity and transition metal ion binding activity. Involved in cell envelope organization and establishment of skin barrier. Located in cornified envelope; keratohyalin granule; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Jan 2025]
Gene Loss events - HRNR (3 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_5AGHXZ | Tursiops truncatus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1038/s41598-021-91863-3 |
| GL_5BLPK6 | Balaenoptera acutorostrata | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1038/s41598-021-91863-3 |
| GL_VHGYQJ | Phocoena sinus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1038/s41598-021-91863-3 |