Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| ODAPH odontogenesis associated phosphoprotein | AI2A4 , C4orf26 | Homo sapiens | 5 | protein-coding | 614829 |
Summary
Dental enamel forms the outer cap of teeth and is the hardest substance found in vertebrates. This gene is thought to encode an extracellular matrix acidic phosphoprotein that has a function in enamel mineralization during amelogenesis. Mutations in this gene are associated with recessive hypomineralized amelogenesis imperfecta. [provided by RefSeq, Oct 2012]
Gene Loss events - ODAPH (13 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_QKJRPT | Eubalaena australis | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1016/j.ympev.2022.107463 |
| GL_UHZ0BI | Megaptera novaeangliae | Artiodactyla | Gene deletion | Full | No | 10.1016/j.ympev.2022.107463 |
| GL_YLGXGQ | Caperea marginata | Artiodactyla | Gene deletion | Full | No | 10.1016/j.ympev.2022.107463 |