Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| LCE1A late cornified envelope 1A | LEP1 | Homo sapiens | 1 | protein-coding | 612603 |
Summary
LCE1A belongs to the late cornified envelope (LCE) gene cluster within the epidermal differentiation complex (EDC) on chromosome 1. The LCE cluster contains multiple conserved genes that encode stratum corneum proteins, and these genes are expressed relatively late during fetal assembly of the skin cornified envelope (Jackson et al., 2005 [PubMed 15854049]). For further information on the LCE gene cluster, see GENE FAMILY below.[supplied by OMIM, Feb 2009]
Gene Loss events - LCE1A (3 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_AM0YQA | Phocoena sinus | Artiodactyla | Other | Full | No | 10.1038/s41598-021-91863-3 |
| GL_JPLWVK | Tursiops truncatus | Artiodactyla | Other | Full | No | 10.1038/s41598-021-91863-3 |
| GL_V0FUEK | Balaenoptera acutorostrata | Artiodactyla | Other | Full | No | 10.1038/s41598-021-91863-3 |