Gene Loss

Reference Gene

Gene name	Alias	Species	Exons	Type	Paralogs	EC number	OMIM
LYG2 lysozyme g2	LYGH , LYGA2 , LYSG2	Homo sapiens	7	protein-coding		3.2.1.17	616547

Summary

The protein encoded by this gene contains a SLT domain, a protein domain present in bacterial lytic transglycosylase (SLT) and in eukaryotic lysozymes (GEWL). SLT domain catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyglucosamine (GlcNAc). [provided by RefSeq, Jul 2008]

GeneOntology

Function (1)

Go ID	Value	Evidence
0003796	enables lysozyme activity	IBA

Component (2)

Go ID	Value	Evidence
0005576	is_active_in extracellular region	IBA
0005576	located_in extracellular region	IDA

Process (4)

Go ID	Value	Evidence
0050830	involved_in defense response to Gram-positive bacterium	IBA
0050830	involved_in defense response to Gram-positive bacterium	IDA
0042742	involved_in defense response to bacterium	IDA
0009253	involved_in peptidoglycan catabolic process	IEA

Gene Loss events - LYG2 (46 results)

GL_ID	Species	Order	Gene Loss Mechanism	Loss Type	Lineage Specific	Citation
GL_WUHCLV	Macroglossus sobrinus	Chiroptera	Gene deletion	Full	No	10.1093/gbe/evab201
GL_X7VWZO	Orcinus orca	Artiodactyla	LOF (frameshift, premature stop, ss)	Full	No	10.1093/gbe/evab201
GL_YORZKL	Globicephala melas	Artiodactyla	LOF (frameshift, premature stop, ss)	Full	No	10.1093/gbe/evab201
GL_YP2XIY	Eubalaena japonica	Artiodactyla	Gene deletion	Undetermined	No	10.1093/gbe/evab201
GL_ZLEUH7	Phocoena phocoena	Artiodactyla	LOF (frameshift, premature stop, ss)	Full	No	10.1093/gbe/evab201
GL_ZRE5DQ	Sousa chinensis	Artiodactyla	LOF (frameshift, premature stop, ss)	Full	No	10.1093/gbe/evab201