Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| SLC22A6 solute carrier family 22 member 6 | OAT1 , PAHT , HOAT1 , ROAT1 | Homo sapiens | 10 | protein-coding | SLC22A23 , SLC22A17 , SLC22A31 , SLC22A15 , SLC22A16 , SLC22A3 , SLC22A1 , SLC22A2 , SLC22A24 , SLC22A9 , SLC22A25 , SLC22A10 , SLC22A11 , SLC22A12 , SLC22A20P , SLC22A8 , SLC22A5 , SLC22A4 , SLC22A7 , SLC22A14 , SLC22A13 , SVOPL , SVOP | 607582 |
Summary
The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Loss events - SLC22A6 (2 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_3XASGY | Pteropus vampyrus | Chiroptera | Exon(s) deletion | Full | No | 10.1038/s41467-018-03667-1 |
| GL_SHUQ1D | Pteropus alecto | Chiroptera | Exon(s) deletion | Full | No | 10.1038/s41467-018-03667-1 |