Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| SERPINA10 serpin family A member 10 | PZI , ZPI | Homo sapiens | 6 | protein-coding | SERPINA9 , SERPINA7 , SERPINA12 , SERPINA11 , SERPINA13P , SERPINA4 , SERPINA5 , SERPINA3 , SERPINA6 , SERPINA2 , SERPINA1 , AGT , SERPINC1 , SERPINF1 , SERPINH1 , SERPIND1 , SERPINE1 , SERPINI2 , SERPINI1 , SERPINF2 , SERPING1 , SERPINB8 , SERPINB9 , SERPINB6 , SERPINE2 , SERPINE3 , SERPINB5 , SERPINB12 , SERPINB13 , SERPINB3 , SERPINB4 , SERPINB2 , SERPINB10 , SERPINB7 , SERPINB11 , SERPINB1 | 605271 |
Summary
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2010]
Gene Loss events - SERPINA10 (1 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_09TTNY | Canis lupus familiaris | Carnivora | Other | Full | No | 10.1038/s41467-018-03667-1 |