Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| MOGAT2 monoacylglycerol O-acyltransferase 2 | hDC5 , MGAT2 , DGAT2L5 , DGAT2L5. | Homo sapiens | 8 | protein-coding | MOGAT3 , DGAT2 , MOGAT1 , AWAT2 , AWAT1 , DGAT2L6 | 2.3.1.20 , 2.3.1.22 | 610270 |
Summary
The protein encoded by this gene is an enzyme that catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. The encoded protein is important in the uptake of dietary fat by the small intestine. This protein forms a complex with diacylglycerol O-acyltransferase 2 in the endoplasmic reticulum, and this complex catalyzes the synthesis of triacylglycerol. [provided by RefSeq, Dec 2015]
Gene Loss events - MOGAT2 (2 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_D87JY1 | Pteropus alecto | Chiroptera | LOF (frameshift, premature stop, ss) | Full | No | 10.1038/s41467-018-03667-1 |
| GL_SMB56E | Pteropus vampyrus | Chiroptera | LOF (frameshift, premature stop, ss) | Full | No | 10.1038/s41467-018-03667-1 |