Gene Loss

Reference Gene

Gene name	Alias	Species	Exons	Type	Paralogs	EC number	OMIM
TAS2R10 taste 2 receptor member 10	TRB2 , T2R10	Homo sapiens	1	protein-coding	TAS2R16 , TAS2R60 , TAS2R41 , TAS2R30 , TAS2R36 , TAS2R33 , TAS2R19 , TAS2R20 , TAS2R50 , TAS2R45 , TAS2R43 , TAS2R31 , TAS2R46 , TAS2R8 , TAS2R13 , TAS2R14 , TAS2R9 , TAS2R42 , TAS2R7 , TAS2R4 , TAS2R38 , TAS2R3 , TAS2R5 , TAS2R1 , TAS2R40 , TAS2R39		604791

Summary

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]

GeneOntology

Go ID	Value	Evidence
0004930	enables G protein-coupled receptor activity	IEA

Go ID	Value	Evidence
0016020	is_active_in membrane	IBA
0016020	located_in membrane	IC
0005886	located_in plasma membrane	TAS

Go ID	Value	Evidence
0007186	involved_in G protein-coupled receptor signaling pathway	IEA
0001580	involved_in detection of chemical stimulus involved in sensory perception of bitter taste	IDA

Gene Loss events - TAS2R10 (1 results)

GL_ID	Species	Order	Gene Loss Mechanism	Loss Type	Lineage Specific	Citation
GL_M2OPBQ	Bos taurus	Artiodactyla	LOF (frameshift, premature stop, ss)	Full	No	10.1186/s40851-014-0002-z

Reference Gene

Summary

GeneOntology

Function (1)

Component (3)

Process (2)

Gene Loss events - TAS2R10 (1 results)