Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
NEU2 neuraminidase 2 SIAL2 Homo sapiens 2 protein-coding OXT , NEU1 , NEU3 , NEU2 , OXT , NEU1 , NEU3 , NEU4 3.2.1.18 605528

Summary

This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments. [provided by RefSeq, Jul 2008]

GeneOntology

Gene Loss events - NEU2 (8 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_7O1JUE Physeter catodon Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1038/s41598-020-68106-y
GL_BBU1QY Balaenoptera acutorostrata Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1038/s41598-020-68106-y
GL_BN7QES Tursiops truncatus Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1038/s41598-020-68106-y
GL_GK0PEW Lipotes vexillifer Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1038/s41598-020-68106-y
GL_K8N5CX Balaena mysticetus Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1038/s41598-020-68106-y
GL_MEC8SX Orcinus orca Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1038/s41598-020-68106-y
GL_NHAIGU Delphinapterus leucas Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1038/s41598-020-68106-y
GL_ODZU6R Fukomys damarensis Rodentia LOF (frameshift, premature stop, ss) Polymorphic No 10.1038/s41598-020-68106-y