Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| IMPG1 interphotoreceptor matrix proteoglycan 1 | RP91 , VMD4 , GP147 , SPACR , IPM150 | Homo sapiens | 17 | protein-coding | 602870 |
Summary
This gene encodes a protein that is a major component of the retinal interphotoreceptor matrix. The encoded protein is a proteoglycan that is thought to play a role in maintaining viability of photoreceptor cells and in adhesion of the neural retina to the retinal pigment epithelium. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
GeneOntology
Gene Loss events - IMPG1 (9 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_0QJMFV | Physeter catodon | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_CDAMWQ | Otolemur garnettii | Primates | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_FXK30Y | Octodon degus | Rodentia | Gene deletion | Full | No | 10.1093/icb/icy004 |
| GL_NBV1TZ | Manis javanica | Pholidota | Gene deletion | Full | No | 10.1093/icb/icy004 |
| GL_OGCFV1 | Fukomys damarensis | Rodentia | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_OO4KLT | Chrysochloris asiatica | Afrosoricida | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_REQBXZ | Condylura cristata | Eulipotyphla | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_VL4JHJ | Nannospalax galili | Rodentia | Gene deletion | Full | No | 10.1093/icb/icy004 |
| GL_XTWYAS | Sorex araneus | Eulipotyphla | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |