Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
PPEF2 protein phosphatase with EF-hand domain 2 PPP7CB Homo sapiens 17 protein-coding PPEF1 , PPP5C 3.1.3.16 602256

Summary

This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein, which is expressed specifically in photoreceptors and the pineal, has been suggested to play a role in the visual system. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. [provided by RefSeq, Jul 2008]

GeneOntology

Gene Loss events - PPEF2 (7 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_CTGEO8 Fukomys damarensis Rodentia Gene deletion Full No 10.1093/icb/icy004
GL_DMDDHR Chrysochloris asiatica Afrosoricida Gene deletion Full No 10.1093/icb/icy004
GL_NCERUV Sorex araneus Eulipotyphla Gene deletion Full No 10.1093/icb/icy004
GL_PX4WCW Nannospalax galili Rodentia LOF (frameshift, premature stop, ss) Full No 10.1093/icb/icy004
GL_XBPHAT Miniopterus natalensis Chiroptera LOF (frameshift, premature stop, ss) Full No 10.1093/icb/icy004
GL_XDTRKK Rhinolophus sinicus Chiroptera Gene deletion Full No 10.1093/icb/icy004
GL_XM5DG9 Manis javanica Pholidota LOF (frameshift, premature stop, ss) Full No 10.1093/icb/icy004