Gene Loss

Reference Gene

Gene name	Alias	Species	Exons	Type	Paralogs	EC number	OMIM
PRCD photoreceptor disc component	RP36	Homo sapiens	10	protein-coding			610598

Summary

This gene is predominantly expressed in the retina, and mutations in this gene are the cause of autosomal recessive retinal degeneration in both humans and dogs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]

GeneOntology

Function (1)

Go ID	Value	Evidence
0002046	enables opsin binding	IBA

Component (6)

Go ID	Value	Evidence
0005794	located_in Golgi apparatus	IDA
0005737	located_in cytoplasm	IDA
0005783	located_in endoplasmic reticulum	IDA
0005576	located_in extracellular region	IDA
0042622	is_active_in photoreceptor outer segment membrane	IBA
0042622	located_in photoreceptor outer segment membrane	IDA

Process (1)

Go ID	Value	Evidence
0007601	involved_in visual perception	IEA

Gene Loss events - PRCD (3 results)

GL_ID	Species	Order	Gene Loss Mechanism	Loss Type	Lineage Specific	Citation
GL_30SU3G	Chrysochloris asiatica	Afrosoricida	Gene deletion	Full	No	10.1093/icb/icy004
GL_BJUS0J	Erinaceus europaeus	Eulipotyphla	Gene deletion	Full	No	10.1093/icb/icy004
GL_GVKNUZ	Condylura cristata	Eulipotyphla	Gene deletion	Full	No	10.1093/icb/icy004