Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| GJA10 gap junction protein alpha 10 | CX62 | Homo sapiens | 1 | protein-coding | GJA5 , GJA5 , GJB4 , GJB4 , GJB5 , GJB5 , GJD3 , GJD3 , GJB7 , GJB7 , GJD2 , GJD2 , GJE1 , GJE1 , GJC1 , GJC1 , GJA8 , GJA8 , GJB6 , GJB6 , GJB2 , GJB2 , GJC3 , GJC3 , GJC2 , GJC2 , GJA4 , GJA4 , GJA3 , GJA3 , GJA1 , GJA1 , GJB1 , GJB1 , GJA10 , GJB3 , GJD4 , GJA10 , GJA10 , GJA5 , GJA5 , GJB4 , GJB4 , GJB5 , GJB5 , GJD3 , GJD3 , GJB7 , GJB7 , GJD2 , GJD2 , GJE1 , GJE1 , GJC1 , GJC1 , GJA8 , GJA8 , GJB6 , GJB6 , GJB2 , GJB2 , GJC3 , GJC3 , GJC2 , GJC2 , GJA4 , GJA4 , GJA3 , GJA3 , GJA1 , GJA1 , GJB1 , GJB1 , GJA9 , GJA9 , GJA9 , GJB3 , GJD4 | 611924 |
Summary
Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008]
GeneOntology
Gene Loss events - GJA10 (15 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_PEAEGI | Chrysochloris asiatica | Afrosoricida | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_SVKEKB | Heterocephalus glaber | Rodentia | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_SZHJO1 | Echinops telfairi | Gene deletion | Full | No | 10.1093/icb/icy004 | |
| GL_YB6E2K | Rhinolophus sinicus | Chiroptera | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_ZJ6D7U | Balaenoptera acutorostrata | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |