Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| OPA3 outer mitochondrial membrane lipid metabolism regulator OPA3 | MGA3 | Homo sapiens | 4 | protein-coding | 606580 |
Summary
The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
GeneOntology
Gene Loss events - OPA3 (2 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_SGVVYK | Canis lupus familiaris | Carnivora | Gene deletion | Full | No | 10.1093/icb/icy004 |
| GL_YAWUZD | Carlito syrichta | Primates | Gene deletion | Full | No | 10.1093/icb/icy004 |