Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| FSCN2 fascin actin-bundling protein 2, retinal | RFSN , RP30 | Homo sapiens | 8 | protein-coding | FSCN3 , FSCN1 | 607643 |
Summary
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneOntology
Gene Loss events - FSCN2 (1 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_UYWMOR | Condylura cristata | Eulipotyphla | Gene deletion | Full | No | 10.1093/icb/icy004 |