Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| GABRR1 gamma-aminobutyric acid type A receptor subunit rho1 | Homo sapiens | 13 | protein-coding | ZACN , HTR3B , HTR3A , CHRNA9 , HTR3C , HTR3D , HTR3E , CHRNA10 , CHRNG , CHRNB1 , CHRND , CHRNE , CHRNB4 , CHRNB2 , CHRNB3 , CHRNA5 , CHRNA3 , CHRNA6 , CHRNA4 , CHRNA1 , CHRNA2 , CHRFAM7A , CHRNA7 , GABRE , GABRG3 , GABRG1 , GABRG2 , GABRA2 , GABRA3 , GABRA5 , GABRA1 , GABRA4 , GABRA6 , GABRD , GABRQ , GABRP , GABRB1 , GABRB3 , GABRR2 , GABRR3 , GABRB2 , GLRB , GLRA2 , GLRA1 , GLRA3 | 137161 |
Summary
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
GeneOntology
Gene Loss events - GABRR1 (2 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_AOPCWX | Chrysochloris asiatica | Afrosoricida | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_RDVOBS | Orycteropus afer | Tubulidentata | Gene deletion | Full | No | 10.1093/icb/icy004 |