Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| KLRF2 killer cell lectin like receptor F2 | NKp65 | Homo sapiens | 6 | protein-coding | 618814 |
Summary
Enables protein homodimerization activity. Predicted to be involved in natural killer cell degranulation and positive regulation of cytokine production. Predicted to act upstream of or within natural killer cell activation and positive regulation of natural killer cell mediated cytotoxicity. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
GeneOntology
Gene Loss events - KLRF2 (5 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_7VVM9P | Physeter catodon | Artiodactyla | Other | Full | No | 10.1016/j.cub.2021.02.057 |
| GL_BHWJQ5 | Hippopotamus amphibius | Artiodactyla | Other | Full | No | 10.1016/j.cub.2021.02.057 |
| GL_KVEPWY | Tursiops truncatus | Artiodactyla | Other | Full | No | 10.1016/j.cub.2021.02.057 |
| GL_SH9IQO | Balaenoptera acutorostrata | Artiodactyla | Other | Full | No | 10.1016/j.cub.2021.02.057 |
| GL_YHXJLX | Orcinus orca | Artiodactyla | Other | Full | No | 10.1016/j.cub.2021.02.057 |