Gene Loss

Reference Gene

Gene name	Alias	Species	Exons	Type	Paralogs	EC number	OMIM
TAS2R9 taste 2 receptor member 9	T2R9 , TRB6	Homo sapiens	1		TAS2R13 , TAS2R14 , TAS2R36 , TAS2R33 , TAS2R19 , TAS2R20 , TAS2R50 , TAS2R45 , TAS2R43 , TAS2R31 , TAS2R30 , TAS2R46 , TAS2R10 , TAS2R42 , TAS2R8 , TAS2R7 , TAS2R38 , TAS2R3 , TAS2R4 , TAS2R5 , TAS2R1 , TAS2R41 , TAS2R60 , TAS2R16 , TAS2R40 , TAS2R39		604795

Summary

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]

GeneOntology

Go ID	Value	Evidence
0004930	enables G protein-coupled receptor activity	IEA

Go ID	Value	Evidence
0016020	is_active_in membrane	IBA
0005886	located_in plasma membrane	TAS

Go ID	Value	Evidence
0007186	involved_in G protein-coupled receptor signaling pathway	IEA
0008150	involved_in biological_process	ND
0001580	involved_in detection of chemical stimulus involved in sensory perception of bitter taste	IBA

Gene Loss events - TAS2R9 (3 results)

GL_ID	Species	Order	Gene Loss Mechanism	Loss Type	Lineage Specific	Citation
GL_AB7WV1	Pan paniscus	Primates	LOF (frameshift, premature stop, ss)	Full	No	10.1093/molbev/msi027
GL_RM8SRX	Gorilla gorilla	Primates	LOF (frameshift, premature stop, ss)	Full	No	10.1093/molbev/msi027
GL_VGRCOU	Papio hamadryas	Primates	LOF (frameshift, premature stop, ss)	Full	No	10.1093/molbev/msi027

Reference Gene

Summary

GeneOntology

Function (1)

Component (2)

Process (3)

Gene Loss events - TAS2R9 (3 results)