Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| KRT28 keratin 28 | KRT25D , K25IRS4 | Homo sapiens | 8 | protein-coding | BFSP2 , KRT18 , KRT24 , KRT23 , KRT33B , KRT34 , LOC100653049 , KRT33A , KRT31 , KRT40 , KRT38 , KRT37 , KRT39 , KRT35 , KRT32 , KRT36 , KRT19 , KRT27 , KRT25 , KRT26 , KRT10 , KRT12 , KRT17 , KRT20 , KRT16 , KRT14 , KRT9 , KRT15 , KRT13 | 616677 |
Summary
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
Gene Loss events - KRT28 (6 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_25IMWY | Balaenoptera acutorostrata | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_2RWOFK | Balaena mysticetus | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_51WL4W | Lipotes vexillifer | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_C8DZDZ | Tursiops truncatus | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_K1CVXR | Neophocaena asiaeorientalis asiaeorientalis | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_XHTCI0 | Orcinus orca | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |