Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| KRT40 keratin 40 | K40 , KA36 , CK-40 | Homo sapiens | 10 | protein-coding | BFSP2 , KRT18 , KRT24 , KRT23 , KRT33B , KRT34 , LOC100653049 , KRT33A , KRT31 , KRT38 , KRT37 , KRT39 , KRT35 , KRT32 , KRT36 , KRT19 , KRT27 , KRT28 , KRT25 , KRT26 , KRT10 , KRT12 , KRT17 , KRT20 , KRT16 , KRT14 , KRT9 , KRT15 , KRT13 | 616679 |
Summary
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
GeneOntology
Gene Loss events - KRT40 (6 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_GXVDFT | Neophocaena asiaeorientalis asiaeorientalis | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_OMKXHB | Balaena mysticetus | Artiodactyla | Other | Full | No | 10.1186/s12983-017-0225-x |
| GL_QPHYDG | Balaenoptera acutorostrata | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1186/1471-2164-15-869 |
| GL_WCMFMC | Lipotes vexillifer | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |
| GL_XDF1KJ | Physeter catodon | Artiodactyla | Other | Full | No | 10.1186/s12983-017-0225-x |
| GL_XEOAJF | Orcinus orca | Artiodactyla | Gene deletion | Full | No | 10.1186/s12983-017-0225-x |