Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
TMPRSS11F transmembrane serine protease 11F HATL4 Homo sapiens 12 protein-coding TMPRSS4 , HPN , TMPRSS9 , TMPRSS6 , TMPRSS11E , TMPRSS11B , TMPRSS11D , TMPRSS11A , ST14 , TMPRSS7 , TMPRSS5 , TMPRSS15 , PRSS8 , CFI , TMPRSS3 , TMPRSS2 , TMPRSS13 , KLKB1 , F11 , PRSS51 , PRSS55 , PRSS41 , PRSS22 , PRSS27 , TMPRSS12 , PRSS50

Summary

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within regulation of water loss via skin. Located in cell surface. [provided by Alliance of Genome Resources, Apr 2022]

GeneOntology

Gene Loss events - TMPRSS11F (4 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_CGOTNS Balaena mysticetus Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1016/j.celrep.2014.12.008
GL_QILEIK Orcinus orca Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671
GL_VXKBPZ Physeter catodon Artiodactyla LOF (frameshift, premature stop, ss) Full No 10.1093/gbe/evx187
GL_WKW3MU Tursiops truncatus Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671