Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| TGM6 transglutaminase 6 | TG6 , TGY , SCA35 , TGM3L , dJ734P14.3 | Homo sapiens | 13 | protein-coding | TGM2 , TGM4 , EPB42 , TGM7 , TGM5 , TGM3 , F13A1 , TGM1 | 2.3.2.13 | 613900 |
Summary
The protein encoded by this gene belongs to the transglutaminase superfamily. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Mutations in this gene are associated with spinocerebellar ataxia type 35 (SCA35). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
GeneOntology
Gene Loss events - TGM6 (4 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_HF8TKK | Balaenoptera acutorostrata | Artiodactyla | Other | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_TRATHR | Tursiops truncatus | Artiodactyla | Other | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_UGEHGY | Orcinus orca | Artiodactyla | Other | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_X5PHWT | Physeter catodon | Artiodactyla | Other | Full | Cetacea | 10.1126/sciadv.aaw6671 |