Gene Loss

Reference Gene

Gene name	Alias	Species	Exons	Type	Paralogs	EC number	OMIM
SLC47A1 solute carrier family 47 member 1	MATE1	Homo sapiens	17	protein-coding			609832

Summary

This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]

GeneOntology

Function (1)

Go ID	Value	Evidence
0015179	enables L-amino acid transmembrane transporter activity	IMP

Component (5)

Go ID	Value	Evidence
0016324	located_in apical plasma membrane	IDA
0016323	located_in basolateral plasma membrane	IDA
0016020	is_active_in membrane	IBA
0005886	located_in plasma membrane	IDA
0005886	located_in plasma membrane	TAS

Process (13)

Go ID	Value	Evidence
1902475	involved_in L-alpha-amino acid transmembrane transport	IMP
0097638	involved_in L-arginine import across plasma membrane	IMP
1903826	involved_in L-arginine transmembrane transport	IEA
0089718	involved_in amino acid import across plasma membrane	IMP
0015695	involved_in organic cation transport	IBA
0015695	involved_in organic cation transport	IDA
1902600	involved_in proton transmembrane transport	IEA
0015847	involved_in putrescine transport	IDA
0071934	involved_in thiamine transmembrane transport	IEA
0055085	involved_in transmembrane transport	TAS
1990961	involved_in xenobiotic detoxification by transmembrane export across the plasma membrane	IDA
0006855	involved_in xenobiotic transmembrane transport	IEA
0042908	involved_in xenobiotic transport	IMP

Gene Loss events - SLC47A1 (4 results)

GL_ID	Species	Order	Gene Loss Mechanism	Loss Type	Lineage Specific	Citation
GL_DVTGZT	Orcinus orca	Artiodactyla	Other	Full	Cetacea	10.1126/sciadv.aaw6671
GL_QXBATM	Physeter catodon	Artiodactyla	Other	Full	Cetacea	10.1126/sciadv.aaw6671
GL_Y1AKEB	Tursiops truncatus	Artiodactyla	Other	Full	Cetacea	10.1126/sciadv.aaw6671
GL_YFTEMG	Balaenoptera acutorostrata	Artiodactyla	Other	Full	Cetacea	10.1126/sciadv.aaw6671