Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
REG4 regenerating family member 4 GISP , RELP , REG-IV Homo sapiens 7 protein-coding CD302 , REG1B , REG1A , REG3A , REG3G , PLA2R1 , LY75 , MRC2 , MRC1 609846

Summary

Enables heparin binding activity and mannan binding activity. Predicted to act upstream of or within response to bacterium. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

GeneOntology

Gene Loss events - REG4 (8 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_2QCSTM Physeter catodon Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671
GL_JJORUP Orcinus orca Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671
GL_JLFR1B Tursiops truncatus Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671
GL_JZGB6F Loxodonta africana Proboscidea Gene deletion Full Proboscidea 10.7554/eLife.38906
GL_R9JFME Mammut americanum Proboscidea Gene deletion Full Proboscidea 10.7554/eLife.38906
GL_TC0JKC Loxodonta cyclotis Proboscidea Gene deletion Full Proboscidea 10.7554/eLife.38906
GL_TL4WUC Elephas maximus Proboscidea Gene deletion Full Proboscidea 10.7554/eLife.38906
GL_XZQIXH Balaenoptera acutorostrata Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671