Reference Gene

Gene name Alias Species Exons Type Paralogs EC number OMIM
DEFB134 defensin beta 134 Homo sapiens 4 protein-coding

Summary

Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 8p23. [provided by RefSeq, Nov 2014]

GeneOntology

Gene Loss events - DEFB134 (4 results)

GL_ID Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_BAIPKQ Physeter catodon Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671
GL_LMY0N6 Balaenoptera acutorostrata Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671
GL_NFPLSV Orcinus orca Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671
GL_V7IRZG Tursiops truncatus Artiodactyla Other Full Cetacea 10.1126/sciadv.aaw6671