Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| CAPN13 calpain 13 | Homo sapiens | 29 | protein-coding | CAPN15 , CAPN10 , CAPN6 , CAPN5 , CAPN14 , CAPN12 , CAPN1 , CAPN9 , CAPN3 , CAPN8 , CAPN2 , CAPN11 | 610228 |
Summary
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012]
GeneOntology
Gene Loss events - CAPN13 (4 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_BAGOZJ | Physeter catodon | Artiodactyla | Other | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_KPYFZJ | Balaenoptera acutorostrata | Artiodactyla | Other | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_PQVRD5 | Orcinus orca | Artiodactyla | Other | Full | Cetacea | 10.1126/sciadv.aaw6671 |
| GL_VGFCHE | Tursiops truncatus | Artiodactyla | Other | Full | Cetacea | 10.1126/sciadv.aaw6671 |