Ψ KRT2 - Hippopotamus amphibius
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_PAPFT6 | Hippopotamus amphibius | LOF (frameshift, premature stop, ss) | Full | Yes | Genomic |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Functional | "Suprabasal epidermis keratin" | 10.1016/j.cub.2021.02.057 |
| Mutation Description | ""64-85D (exon 1) 785D (exon 2) 1630D (exon 9) 1758D (exon 9)" D = Deletion" | 10.1016/j.cub.2021.02.057 |
| Timing of Loss | "26.41 MA" | 10.1016/j.cub.2021.02.057 |
| Other | ""Eight of nine genes (ALOX15, AWAT1, KPRP, KRT2, KRT26, KRT77, KRTAP7-1, and TCHHL1) exhibit shared inactivating mutations in both hippopotamid species."" | 10.1016/j.cub.2021.02.057 |
Curator Observations
See Table 2 for details regarding timing of loss. See Supplementary Table 2 for details regarding inactivating mutations.