Ψ MOGAT3 - Hippopotamus amphibius

Reference Gene:
Job_ID:
Curator:
GlossID Species Gene Loss Mechanism Loss Type Lineage Specific Evidence Accession Nr.
GL_H4BSOU Hippopotamus amphibius LOF (frameshift, premature stop, ss) Full No Single individual SRA XM_057750897.1

Statements

Type Excerpt DOI
Functional "Thus, two scenarios could be put forward regarding the inactivation of Mogat3. First, it could reflect convergent skin-specific molecular changes, more specifically degeneration of SGs or changes in sebum lipid composition(Nikkari 1974)." 10.1093/molbev/msz068
Functional "Alternatively, Mogat3 loss could be related to dietary adaptations, especially to herbivory, as in the case of T. m. latirostris, C. s. simum and L. africana." 10.1093/molbev/msz068
Mutation Description "Premature stop codonmutations in exon 2 of H. amphibius Mogat3 and exon 3 of Awat1 were further confirmed by SRA (supplementary material 3, Supplementary Material online)." 10.1093/molbev/msz068
Other "Yet, read assembly and analysis of the corresponding transcripts revealed the presence of two distinct transcript types, one corresponding to Mogat3 and the second possibly corresponding to aMogat3-like gene (supplementary material 4, Supplementary Material online)." "The analysis of the transcripts corresponding to the Mogat3-like sequence, revealed no deleterious mutations and probably corresponds to a functional gene (supplementarymaterial 4, supplementaryMaterial online)." 10.1093/molbev/msz068

Related Glosses

GL_ID Symbol Species Order Gene Loss Mechanism Loss Type Lineage Specific Citation
GL_FIIBET MOGAT3 Hippopotamus amphibius Artiodactyla LOF (frameshift, premature stop, ss) Full Hippopotamidae 10.1016/j.cub.2021.02.057