Ψ Cym - Homo sapiens
Reference Gene:
Job_ID:
Curator:
| GlossID | Species | Gene Loss Mechanism | Loss Type | Lineage Specific | Evidence | Accession Nr. |
|---|---|---|---|---|---|---|
| GL_1YXLAO | Homo sapiens | LOF (frameshift, premature stop, ss) | Full | Yes | Multiple individual SRA | NR_003599.2 |
Statements
| Type | Excerpt | DOI |
|---|---|---|
| Mutation Description | "Interestingly, a cross species analysis in Hominoidea and Cercopithecoidea uncovers a conserved single mutation that spans throughout all analysed Cmy-like sequences, namely a termination codon in exon 5. " | 10.1016/j.ympev.2017.08.014 |
| Mutation Description | "The analysis of the Homo sapiens CMYP (OMIM#118943) genomic region, confirmed a frameshift in exon 4 produced by a 1 bp deletion, followed by a termination codon in exon 5, and a second frameshift in exon 6 produced by a 2 bp deletion. " | 10.1016/j.ympev.2017.08.014 |
Curator Observations
In humans Chymosin is a known Pseudogene.