Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| INSL4 insulin like 4 | EPIL , PLACENTIN | Homo sapiens | 2 | protein-coding | INSL6 , RLN1 , RLN2 | 600910 |
Summary
INSL4 encodes the insulin-like 4 protein, a member of the insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the early placental cytotrophoblast and syncytiotrophoblast. [provided by RefSeq, Jul 2008]
GeneOntology
Gene Loss events - INSL4 (34 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_XPEDMD | Camelus bactrianus | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1016/j.ygcen.2017.07.011 |
| GL_YRMMXX | Mustela putorius furo | Carnivora | LOF (frameshift, premature stop, ss) | Full | No | 10.1016/j.ygcen.2017.07.011 |
| GL_YVWGAJ | Physeter catodon | Artiodactyla | LOF (frameshift, premature stop, ss) | Full | No | 10.1016/j.ygcen.2017.07.011 |
| GL_YWRFS8 | Okapia johnstoni | Artiodactyla | Gene deletion | Full | No | 10.1016/j.ygcen.2017.07.011 |