Reference Gene
| Gene name | Alias | Species | Exons | Type | Paralogs | EC number | OMIM |
|---|---|---|---|---|---|---|---|
| EYS eyes shut homolog | RP25 , SPAM , EGFL10 , EGFL11 , C6orf178 , C6orf179 , C6orf180 , bA74E24.1 , dJ22I17.2 , bA166P24.2 , bA307F22.3 , dJ1018A4.2 , dJ303F19.1 | Homo sapiens | 46 | protein-coding | NTNG2 , NTNG1 , LAMC2 | 612424 |
Summary
The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
GeneOntology
Gene Loss events - EYS (19 results)
| GL_ID | Species | Order | Gene Loss Mechanism | Loss Type | Lineage Specific | Citation |
|---|---|---|---|---|---|---|
| GL_PENQHK | Dasypus novemcinctus | Cingulata | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_R2KRPC | Manis javanica | Pholidota | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_S777CB | Fukomys damarensis | Rodentia | Gene deletion | Full | No | 10.1093/icb/icy004 |
| GL_URILHZ | Tupaia chinensis | Scandentia | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_VNYYXH | Mus musculus | Rodentia | Gene deletion | Full | No | 10.1093/icb/icy004 |
| GL_WK9HCE | Miniopterus natalensis | Chiroptera | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_WSMFID | Heterocephalus glaber | Rodentia | Gene deletion | Full | No | 10.1093/icb/icy004 |
| GL_Y2ZR74 | Carlito syrichta | Primates | LOF (frameshift, premature stop, ss) | Full | No | 10.1093/icb/icy004 |
| GL_YWX0IL | Nannospalax galili | Rodentia | Gene deletion | Full | No | 10.1093/icb/icy004 |